Back to search

Article

Deciphering Metabolic Pathways and Protein-Protein Interaction Networks in Ankylosing Spondylitis through Single-Cell RNA Sequencing

2024-10-24

Abstract excerpt

Ankylosing Spondylitis (AS) is a common autoimmune disease affecting spinal joints and causing chronic pain. Understanding the roles of different cell types in AS can facilitate the development of effective treatments. In this study, we analyzed scRNA-seq data of peripheral blood mononuclear cells (PBMC) from AS patients and healthy controls collected from the literature. Using the GIMME algorithm, we created geno...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
2b1a291c-4c10-57e7-9c35-a1966459c634
DOI
10.1101/2024.10.21.619465
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Deciphering Metabolic Pathways and Protein-Protein Interaction Networks in Ankylosing Spondylitis through Single-Cell RNA SequencingDOI 10.1101/2024.10.21.619465
Correction: Integrative multi-omics analyses identify PKD1 and SLC2A4 as genetically supported glycolysis-related candidate genes for rheumatoid arthritis.Semantic proximity
Metabolic reprogramming and macrophage expansion define ACPA-negative rheumatoid arthritis: insights from single-cell RNA sequencingSemantic proximity
Integrative multi-omics analyses identify PKD1 and SLC2A4 as genetically supported glycolysis-related candidate genes for rheumatoid arthritis.Semantic proximity
In Silico Modeling of Metabolic State in Single Th17 Cells Reveals Novel Regulators of Inflammation and AutoimmunitySemantic proximity
The role of lactylation in plasma cells and its impact on rheumatoid arthritis pathogenesis: insights from single-cell RNA sequencing and machine learningSemantic proximity
Exploring T Cell and NK Cell Involvement in Ankylosing Spondylitis Through Single‐Cell SequencingSemantic proximity
BiomiX-Driven Multi-Omics Integration of PRECISESADS Data Reveals Lysophosphatidic Acid and Metabolic Pathway Signatures in B Cells and Immune Macroenvironment in Sjögren’s DiseaseSemantic proximity
Integrating machine learning and multi-omics analysis to reveal nucleotide metabolism-related immune genes and their functional validation in ischemic strokeSemantic proximity
An overview of multi-omics technologies in rheumatoid arthritis: applications in biomarker and pathway discoverySemantic proximity
Differentially expressed protein-coding genes in ankylosing spondylitis: Emerging insights into pathogenesis and therapeutic approaches.Semantic proximity
Identification of Energy Metabolism and m6A-Related Gene Clusters in Kashin-Beck Disease Based on Bioinformatics AnalysisSemantic proximity
Dysregulation of ribosome-related genes in ankylosing spondylitis: a systems biology approach and experimental methodSemantic proximity
Select a neighboring publication to make it the new centre.