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Integrating machine learning and multi-omics analysis to reveal nucleotide metabolism-related immune genes and their functional validation in ischemic stroke

26 Mar 2025

Abstract excerpt

Background Ischemic stroke (IS) is a major global cause of death and disability, linked to nucleotide metabolism imbalances. This study aimed to identify nucleotide metabolism-related genes associated with IS and explore their roles in disease mechanisms for new diagnostic and therapeutic strategies. Methods IS gene expression data were sourced from the GEO database. Differential expression analysis and weighted...

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PMID: 40207230
DOI: 10.3389/fimmu.2025.1561544

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