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Innate lymphoid cells and the MHC

28 Dec 2015

Abstract excerpt

Innate lymphoid cells (ILCs) are a new class of immune cells that include natural killer (NK) cells and appear to be the innate counterparts to CD4(+) helper T cells and CD8(+) cytotoxic T cells based on developmental and functional similarities. Like T cells, both NK cells and other ILCs also show connections to the major histocompatibility complex (MHC). In human and mouse, NK cells recognize and respond to...

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PMID: 26812060
DOI: 10.1111/tan.12723

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