Article

MAP Kinase and mammalian target of rapamycin are main pathways of gallbladder carcinogenesis: Results from bioinformatic analysis of Next Generation Sequencing data from a hospital-based cohort

2022-05-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Gallbladder Cancer (GBC) is one of the most common cancers of the biliary tract and the third commonest gastrointestinal (GI) malignancy worldwide. The disease is characterized by the late presentation and poor outcome despite treatment, and hence, newer therapies and targets need to be identified. <h4>Methods</h4> The current study investigated various functionally enriche...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2ae76686-d9ec-5c25-b1ec-dbbc3dc621b7
DOI: 10.1101/2022.05.11.491590

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MAP Kinase and mammalian target of rapamycin are main pathways of gallbladder carcinogenesis: Results from bioinformatic analysis of Next Generation Sequencing data from a hospital-based cohortDOI 10.1101/2022.05.11.491590Read

MAP kinase and mammalian target of rapamycin are main pathways of gallbladder carcinogenesis: results from bioinformatic analysis of next generation sequencing data from a hospital-based cohort (NCT05404347).Semantic proximity Read

Somatic genetic aberrations in gallbladder cancer: comparison between Chinese and US patientsSemantic proximity Read

Disparities in Gallbladder Cancer: Epidemiology, Molecular Mechanisms, and Clinical Implications.Semantic proximity Read

Identification of Altered Genes in Gallbladder Cancer as Potential Driver Mutations for Diagnostic and Prognostic Purposes: A Computational ApproachSemantic proximity Read

Next generation sequencing uncovers multiple miRNAs associated molecular targets in gallbladder cancer patientsSemantic proximity Read

Genomic profiling of gallbladder carcinoma: Targetable mutations and pathways involved.Semantic proximity Read

Stepwise correlation of TP53 mutations from pancreaticobiliary maljunction to gallbladder carcinoma: a retrospective study.Semantic proximity Read

Identification of MAP kinase pathways as therapeutic targets in gallbladder carcinoma using targeted parallel sequencing.Semantic proximity Read

Integrative proteogenomic analysis provides molecular insights and clinical significance in gallbladder cancer.Semantic proximity Read

RNA sequencing reveals differentially expressed genes as potential diagnostic and prognostic indicators of gallbladder carcinomaSemantic proximity Read

Targeted-Gene Sequencing and Bioinformatics Analysis of Patients with Gallbladder Neuroendocrine Carcinoma: A Case Report and Literature ReviewSemantic proximity Read

Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention.Semantic proximity Read