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Article

Stepwise correlation of TP53 mutations from pancreaticobiliary maljunction to gallbladder carcinoma: a retrospective study.

BMC cancer - 19 Nov 2021

Kawakami Satoshi, Takano Shinichi, Fukasawa Mitsuharu, Shindo Hiroko, Takahashi Ei, Fukasawa Yoshimitsu, Hayakawa Hiroshi, Kuratomi Natsuhiko, Kadokura Makoto, Hosomura Naohiro, Amemiya Hidetake, Kawaida Hiromichi, Kono Hiroshi, Maekawa Shinya, Ichikawa Daisuke, Enomoto Nobuyuki

Abstract excerpt

BACKGROUND: The genetic changes underlying carcinogenesis in patients with risk factors of gallbladder carcinoma (GBC) remains controversial, especially in patients with pancreaticobiliary maljunction (PBM). This study aimed to clarify the association between risk factors of GBC and genetic changes using next-generation sequencing (NGS). METHODS: We retrospectively analyzed resected tissues of 64 patients who...

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Identifiers

PMID: 34798839
DOI: 10.1186/s12885-021-09000-2
PMCID: PMC8605550

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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