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The results of Transcriptome-wide Mendelian Randomization (TWMR) in large-scale populations can directly validate, across scales, the results of causal inference from deep learning combined with double machine learning on single-cell transcriptomes of human samples

2026-03-19

Abstract excerpt

<title>Abstract</title> <p> <bold>Objective</bold> Aiming at the core problems prevalent in biomedical research, including the "translational distance", the difficulty in aligning cross-scale studies, and the lack of direct validation of single-cell systems biology models in human samples, this study aims to verify whether the results of transcriptome-wide Mendelian randomization (TWMR) based on large-scale pop...

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Literature Corpus work
2aa90c6e-8750-5ca2-95e7-b6c590c47a59
DOI
10.21203/rs.3.rs-9151722/v1
Open publication

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The results of Transcriptome-wide Mendelian Randomization (TWMR) in large-scale populations can directly validate, across scales, the results of causal inference from deep learning combined with double machine learning on single-cell transcriptomes of human samplesDOI 10.21203/rs.3.rs-9151722/v1
The results of Transcriptome-wide Mendelian Randomization (TWMR) in large-scale populations can directly validate, across scales, the results of causal inference from deep learning combined with double machine learning on single-cell transcriptomes of human samplesSemantic proximity
The results of Transcriptome-wide Mendelian Randomization (TWMR) in large-scale populations can directly validate, across scales, the results of causal inference from deep learning combined with double machine learning on single-cell transcriptomes of human samplesSemantic proximity
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