Back to search

Article

Multiscale Metabolic Covariance Networks Uncover Stage-Specific Biomarker Signatures Across the Alzheimer’s Disease Continuum

2025-07-15

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Connectomics studies analyze neural connections and their roles in cognition and disease. Beyond regional comparisons, recent research has revealed inter-regional brain relationships via graph theory of brain network connectivity. Within these networks, path length measures a network’s efficiency in communication. These connections can be quantified as inter-subject covarian...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
2a1855ba-f44d-5eff-821c-0673f20ba659
DOI
10.1101/2025.07.10.663714
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Multiscale Metabolic Covariance Networks Uncover Stage-Specific Biomarker Signatures Across the Alzheimer’s Disease ContinuumDOI 10.1101/2025.07.10.663714
Brain Metabolic Network Covariance and Aging in a Mouse Model of Alzheimer’s DiseaseSemantic proximity
Dysfunction in the hierarchy of morphometric similarity network in Alzheimer’s disease and its correlation with cognitive performance and gene expression profilesSemantic proximity
Multiscale networks in Alzheimer’s disease identify brain hypometabolism as central across biological scalesSemantic proximity
Morphological connectivity differences in Alzheimer's disease correlate with gene transcription and cell‐typeSemantic proximity
Human brain connectome profiles mediate the relationship between pathology burden and clinical phenotypes in Alzheimer's disease.Semantic proximity
Metabolism-weighted brain connectome reveals synaptic integration and vulnerability to neurodegenerationSemantic proximity
Identification of abnormal lipid profiles promote cognitive decline in Alzheimer’s disease spectrum via large-scale brain connectivitySemantic proximity
Multiplex connectome changes across the alzheimer’s disease spectrum using gray matter and amyloid dataSemantic proximity
Multimodal Fusion Analysis of [18F]Florbetapir PET and Multiscale Functional Network Connectivity in Alzheimer’s DiseaseSemantic proximity
White matter dysfunction in Alzheimer’s disease is associated with disease-related transcriptomic signaturesSemantic proximity
Exploratory Correlation of The Human Structural Connectome with Non-MRI Variables in Alzheimer’s DiseaseSemantic proximity
In Alzheimer-prone brain regions, metabolism and risk-gene expression are strongly correlatedSemantic proximity
Select a neighboring publication to make it the new centre.