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In Alzheimer-prone brain regions, metabolism and risk-gene expression are strongly correlated

25 Aug 2022

Abstract excerpt

Abstract Neuroimaging in the preclinical phase of Alzheimer’s disease provides information crucial to early intervention, particularly in people with a high genetic risk. Metabolic network modularity, recently applied to the study of dementia, is increased in Alzheimer’s disease patients compared with controls, but network modularity in cognitively unimpaired elderly with various risks of developing Alzheimer’s...

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PMID: 36092303
DOI: 10.1093/braincomms/fcac216

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