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Knocking-down of CYP2C9 expression in Huh-7 and HepG2 cells using CRISPR/Cas9 method

2023-10-06

Abstract excerpt

The emergence of CRISPR/Cas system allows for precise and efficient alteration of genetic sequences in almost any kind of living cells. Several studies have attempted to modify human hepatocytes with plasmids that encodes immortalized genes, such as hepatocytes derived from stem cells or cell lines produced by an organism. Most strategies are time consuming and requires high technical expertise, especially for the...

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Literature Corpus work
29f2cb02-6a4e-554c-aa74-9f293410124f
DOI
10.22541/au.169661561.14446149/v1
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