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Description of CRISPR/Cas9 development and its prospect in hepatocellular carcinoma treatment

1 Jun 2020

Abstract excerpt

Hepatocellular carcinoma (HCC) is one of the most common malignancies today. Patients suffer from HCC since its high malignancy and limited treatment means. With the development of genetic research, new therapeutic strategy comes up in the way of gene editing. Clustered regularly interspaced short palindromic repeat/CRISPR-associated nuclease 9 (CRISPR/Cas9) was discovered as an immune sequence in bacteria and...

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PMID: 32487115
DOI: 10.1186/s13046-020-01603-0

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