Article

The Chemistry of Fentanyl and Its Implications on Brain Development: A Review

2026-04-03

Abstract excerpt

<title>Abstract</title> <p>Since its discovery in 1960 by Paul Janssen, fentanyl has emerged as one of the central substances in the global opioid crisis because of its high potency (50–100 times that of morphine) and rapid penetration through the blood-brain barrier. Following the PRISMA 2020 guidelines for reporting systematic reviews and meta-analyses, this systematic review synthesizes the results of ten empi...

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Literature Corpus work: 29e8ddac-19a9-511e-8920-ca353d86714d
DOI: 10.21203/rs.3.rs-9288777/v1

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