Article

Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction

2023-06-26

Abstract excerpt

Despite the high prevalence of heart failure in the western world, there are few effective treatments. Fibulin-3 is a protein involved in extracellular matrix (ECM) structural integrity, however its role in the heart is unknown. We have demonstrated, using single cell RNA-seq, that fibulin-3 was highly expressed in quiescent murine cardiac fibroblasts, with expression highest prior to injury and late post-infarct...

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Literature Corpus work: 29830edb-70bb-57ca-bf24-2fe9ea38a398
DOI: 10.21203/rs.3.rs-3055737/v1

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