Article
UGGT1 mediates N-glycosylation of LGALS3BP to induce angiogenesis in liver cancer via the NOTCH signaling pathway
2025-11-24
Abstract excerpt
<title>Abstract</title> <p> Background Liver cancer (LC) is one of the leading causes of cancer-related deaths worldwide. Its complex vascular regulatory network and drug resistance severely limit clinical efficacy. Although LGALS3BP is highly expressed in various malignant tumors, its biological function and molecular regulatory mechanisms in LC angiogenesis remain to be elucidated. Methods Bioinformatics analy...
Topics
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- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Glycosylation and Glycoproteins Research
- interferon and immune responses
- Liver physiology and pathology
- MicroRNA in disease regulation
- Proteoglycans and glycosaminoglycans research
- Wnt/β-catenin signaling in development and cancer
Identifiers and source
- Literature Corpus work
- 29756fcc-5c40-5734-a5e9-96b73b257f03
- DOI
- 10.21203/rs.3.rs-8052281/v1
