Article

GSG2 Promotes Tumor Growth Through Regulating Cell Proliferation in Hepatocellular Carcinoma

2021-09-09

Abstract excerpt

<title>Abstract</title> <p>BackgroundHepatocellular carcinoma (HCC) is one of the most commonly diagnosed malignant tumors in the world, and its recurrence and mortality rate are still in high level. In recent years, more and more inhibitors against gene targets have been found to be beneficial to survival. However, the function of homo-sapiens histone H3 associated protein kinase (GSG2) in HCC has not been compl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0d05f129-a763-5a91-a3c4-92c124565a5a
DOI: 10.21203/rs.3.rs-880139/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

GSG2 Promotes Tumor Growth Through Regulating Cell Proliferation in Hepatocellular CarcinomaDOI 10.21203/rs.3.rs-880139/v1Read

Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinomaSemantic proximity Read

Upregulation of SGOL2 Predicts Poor Prognosis and Facilitates Hepatocellular Carcinoma Progression via Dysregulating the Cell Cycle by Directly Activating MAD2Semantic proximity Read

Growth inhibition of human hepatocellular carcinoma cells by overexpression of G-protein-coupled receptor kinase 2.Semantic proximity Read

Cyclin-Dependent Kinase Regulatory Subunit 2 Indicated Poor Prognosis and Facilitated Aggressive Phenotype of Hepatocellular Carcinoma.Semantic proximity Read

SGOL2 is a novel prognostic marker and fosters disease progression via a MAD2-mediated pathway in hepatocellular carcinomaSemantic proximity Read

LASP2 is downregulated in human liver cancer and contributes to hepatoblastoma cell malignant phenotypes through MAPK/ERK pathway.Semantic proximity Read

The survival prediction analysis and preliminary study of the biological function of YEATS2 in hepatocellular carcinomaSemantic proximity Read

shRNA‐mediated silencing of Gli2 gene inhibits proliferation and sensitizes human hepatocellular carcinoma cells towards TRAIL‐induced apoptosisSemantic proximity Read

Proteomic study of hepatic apoptosis induced by overexpression of G0S2Semantic proximity Read

ESCO2 promotes the proliferation of hepatocellular carcinoma through PI3K/AKT/ mTOR signaling pathwaySemantic proximity Read

Correlation of LAGE3 with unfavorable prognosis and promoting tumor development in HCC via PI3K/AKT/mTOR and Ras/RAF/MAPK pathwaysSemantic proximity Read

Inhibition of WWP2 suppresses proliferation, and induces G1 cell cycle arrest and apoptosis in liver cancer cellsSemantic proximity Read