Article

Enhanced virus detection and metagenomic sequencing in patients with meningitis and encephalitis

2020-11-27

Abstract excerpt

Meningitis and encephalitis are leading causes of central nervous system (CNS) disease and often result in severe neurological compromise or death. Traditional diagnostic workflows largely rely on pathogen-specific diagnostic tests, sometimes over days to weeks. Metagenomic next-generation sequencing (mNGS) is a high-throughput platform that profiles all nucleic acid in a sample. We prospectively enrolled 68 patie...

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Literature Corpus work: b0e719a8-c156-5729-8d89-8f8583a9934a
DOI: 10.1101/2020.11.25.399394

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