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Article

Next-generation sequencing in neuropathological diagnosis of infections of the nervous system

2016-02-09

Abstract excerpt

<h4>Objective</h4> To determine the feasibility of next-generation sequencing (NGS) microbiome approaches in the diagnosis of infectious disorders in brain or spinal cord biopsies in patients with suspected central nervous system (CNS) infections. <h4>Methods</h4> In a prospective-pilot study, we applied NGS in combination with a new computational analysis pipeline to detect the presence of pathogenic microbes i...

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Literature Corpus work
7b84afcf-e929-5bd4-82b3-ae611cbb2efa
DOI
10.1101/039222
Open publication

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Next-generation sequencing in neuropathological diagnosis of infections of the nervous systemDOI 10.1101/039222
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