Article

ENaC contributes to macrophage dysfunction in cystic fibrosis

2024-11-08

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Cystic fibrosis (CF) is a chronic systemic disease caused by dysfunctional or absent cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is expressed in human immune cells and plays a role in regulating innate immunity both directly and indirectly. Besides CFTR, research indicates that the epithelial sodium channel (ENaC) also contributes to dysfunction in CF ai...

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Literature Corpus work: 291b9714-01cb-5f48-9301-b4fcbdf91917
DOI: 10.1101/2024.11.06.622340

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