Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Anti-interferon alpha treatment in SLE.

Clinical immunology (Orlando, Fla.) - 1 Sept 2013

Kirou Kyriakos A, Gkrouzman Elena

Abstract excerpt

Several studies in the last decade have highlighted the role of the type I interferon (IFN-I) pathway, and particularly interferon alpha (IFNα) in SLE pathogenesis. As a result, a multitude of potential treatments targeting IFNα have emerged in the last few years, a few of which have already completed phase II clinical trials. Some of the treatment strategies have focused on blocking IFNα or its receptor and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dendritic Cells
Share to Genetic Predisposition to Disease
Share to Interferon-alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lupus Erythematosus, Systemic

Share to Receptor, Interferon alpha-beta

Share to Signal Transduction

Source

Identifiers

PMID: 23566912
DOI: 10.1016/j.clim.2013.02.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Anti-interferon alpha treatment in SLE.PMID 23566912Read ↗

A Pivotal Role for the Natural Interferon α–producing Cells (Plasmacytoid Dendritic Cells) in the Pathogenesis of LupusSemantic proximity Read ↗

Cause and consequences of the activated type I interferon system in SLESemantic proximity Read ↗

Optimal Selection of IFN-α-Inducible Genes to Determine Type I Interferon Signature Improves the Diagnosis of Systemic Lupus ErythematosusSemantic proximity Read ↗

Interferon-alpha: a therapeutic target in systemic lupus erythematosus.Semantic proximity Read ↗

Potential role of IFNα in adult lupus.Semantic proximity Read ↗

Interferon alpha as a primary pathogenic factor in human lupus.Semantic proximity Read ↗

Unraveling the Link between Interferon-α and Systemic Lupus Erythematosus: From the Molecular Mechanisms to Target TherapiesSemantic proximity Read ↗

Role of interferons in SLESemantic proximity Read ↗

Inhibitor of IκB kinase activity, BAY 11-7082, interferes with interferon regulatory factor 7 nuclear translocation and type I interferon production by plasmacytoid dendritic cellsSemantic proximity Read ↗

Interferon pathway in SLE: one key to unlocking the mystery of the diseaseSemantic proximity Read ↗

Type I interferon and lupusSemantic proximity Read ↗

Systemic lupus erythematosus: all roads lead to type I interferons.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.