Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A systems model for immune cell interactions unravels the mechanism of inflammation in human skin.

PLoS computational biology - 2 Dec 2010

Valeyev Najl V, Hundhausen Christian, Umezawa Yoshinori, Kotov Nikolay V, Williams Gareth, Clop Alex, Ainali Crysanthi, Ouzounis Christos, Tsoka Sophia, Nestle Frank O

Abstract excerpt

Inflammation is characterized by altered cytokine levels produced by cell populations in a highly interdependent manner. To elucidate the mechanism of an inflammatory reaction, we have developed a mathematical model for immune cell interactions via the specific, dose-dependent cytokine production...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dose-Response Relationship, Immunologic
Share to Histocytochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homeostasis

Share to Inflammation

Share to Leukocytes

Share to Psoriasis

Share to Systems Biology

Source

Open in PubMed Open full text

Identifiers

PMID: 21152006
DOI: 10.1371/journal.pcbi.1001024
PMCID: PMC2996319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21152006-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A systems model for immune cell interactions unravels the mechanism of inflammation in human skin.PMID 21152006Read ↗

Modeling of the Network Mediated by IL-36 Involved in PsoriasisSemantic proximity Read ↗

A dynamic Boolean model of molecular and cellular interactions represents psoriasis development and predicts drug candidatesSemantic proximity Read ↗

Mathematical modelling of epithelium homeostasisSemantic proximity Read ↗

Mathematical design of optimal treatment schedules for atopic dermatitis based on a mechanistic modelling approachSemantic proximity Read ↗

Pattern Formation in a Model of InflammationSemantic proximity Read ↗

The competitive nature of signal transducer and activator of transcription complex formation drives phenotype switching of T cells.Semantic proximity Read ↗

Logical and experimental modeling of cytokine and eicosanoid signaling in psoriatic keratinocytesSemantic proximity Read ↗

A mathematical model for immune and autoimmune response mediated by<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si88.gif" display="inline" overflow="scroll"><mml:mi>T</mml:mi></mml:math>-cellsSemantic proximity Read ↗

Bifurcation analysis of a mathematical model of atopic dermatitis to determine patient-specific effects of treatments on dynamic phenotypes.Semantic proximity Read ↗

From Discrete to Continuous Modeling of Lymphocyte Development and Plasticity in Chronic DiseasesSemantic proximity Read ↗

Implementation of a regulatory gene network to simulate the TH1/2 differentiation in an agent-based model of hypersensitivity reactionsSemantic proximity Read ↗

Modeling the role of TGF-β in regulation of the Th17 phenotype in the LPS-driven immune system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.