Article

The role of MEGF10 in myoblast fusion and hypertrophic response to overload of skeletal muscle

2024-10-30

Abstract excerpt

<title>Abstract</title> <p>Biallelic mutations in multiple EGF domain protein 10 (<italic>MEGF10</italic>) gene cause EMARDD (early myopathy, areflexia, respiratory distress and dysphagia) in humans, a severe recessive myopathy, associated with reduced numbers of PAX7 positive satellite cells. To better understand the role of MEGF10 in satellite cells, we overexpressed human MEGF10 in mouse <italic>H-2k</italic><...

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Literature Corpus work: 2918b4ee-895b-5e03-9384-02078e844591
DOI: 10.21203/rs.3.rs-5295425/v1

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