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Article

Comparative study of enriched dopaminergic neurons from siblings with Gaucher disease discordant for parkinsonism

2024-02-28

Abstract excerpt

Inducible pluripotent stem cells (iPSCs) derived from patient samples have significantly enhanced our ability to model neurological diseases. Comparative studies of dopaminergic (DA) neurons differentiated from iPSCs derived from siblings with Gaucher disease discordant for parkinsonism provides a valuable avenue to explore genetic modifiers contributing to GBA1 -associated parkinsonism in disease-relevant cells....

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Literature Corpus work
29144877-9457-59d7-82b8-fddb1809e0c9
DOI
10.1101/2024.02.25.581985
Open publication

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Comparative study of enriched dopaminergic neurons from siblings with Gaucher disease discordant for parkinsonismDOI 10.1101/2024.02.25.581985
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