Article

Human MAP tau based targeted cytolytic fusion proteins

2017-06-15

Abstract excerpt

Some of the most promising small molecule toxins used to generate antibody drug conjugates (ADCs) include anti-mitotic agents (e.g auristatin and its derivatives) which are designed to attack cancerous cells at their most vulnerable state during mitosis. We were interested to identify a human cystostatic protein eventually showing comparable activities and allowing the generation of corresponding targeted fully hu...

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Literature Corpus work: 28c4054b-1b39-51ee-a209-6e2b04435668
DOI: 10.20944/preprints201706.0068.v1

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