Article

Rosindol: A fluorogen for the quantitative measurement of reactive oxygen species in living cells

2026-06-09

Abstract excerpt

Reactive oxygen species (ROS) are key mediators of disease, yet accurate characterization in living systems remains challenging because current probes lack oxidation specificity and produce nonlinear, pH-dependent signals. Here we introduce Rosindol, a novel thioacetal-based fluorogenic probe that overcomes these limitations. Rosindol undergoes an umpolung oxidation in the presence of ROS to generate fluorescence...

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Literature Corpus work: 289aaf7f-1519-55e7-b8e5-b55b1e220f2f
DOI: 10.64898/2026.06.04.730197

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