Article

A Stochastic Simulation-Based Approach to Inform Relapsing Mouse Model (RMM) Study Design for Non-Clinical Assessment of Tuberculosis

2025-07-22

Abstract excerpt

<h4>ABSTRACT</h4> The development of new regimens to treat tuberculosis (TB), the disease caused by Mycobacterium tuberculosis (Mtb), is critical to improving patient outcomes and decreasing global infectious disease mortality. Early evaluation of candidate regimens in non-clinical models of TB, such as the relapsing mouse model (RMM), remains an important step in prioritizing the most efficacious regimens for f...

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Literature Corpus work: 2897b182-4762-552c-bd3f-b1333c5afdba
DOI: 10.1101/2025.07.18.665504

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