Article
Predictive and prognostic factors for immunotherapy response in head and neck squamous cell carcinoma: a narrative review.
Expert review of clinical pharmacology - 1 May 2026
Calabrò Concetta, De Palma Giuseppe, Gheit Tarik, Iacovelli Serena, Mastrandrea Giovanni, Rizzo Alessandro, Palermo Loredana
Abstract excerpt
INTRODUCTION: Immune checkpoint inhibitors (ICIs) have reshaped the therapeutic landscape of head and neck squamous cell carcinoma (HNSCC). However, only a subset of patients derives durable benefit, highlighting the need for reliable predictive factors of response. AREAS COVERED: A literature search was conducted in PubMed/MEDLINE, Scopus, and Web of Science (2015-2026) using relevant keywords. This narrative...
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