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High-Sensitivity PD-L1 Staining Using Clone 73-10 Antibody and Spatial Transcriptomics for Precise Expression Analysis in Non-Tumorous, Intraepithelial neoplasia, and Squamous Cell Carcinoma of Head and Neck

2025-04-07

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<title>Abstract</title> <p><bold>Purpose</bold>: Although immune checkpoint inhibitors (ICIs) have improved the prognosis of head and neck squamous cell carcinoma (HNSCC), certain patients remain ineligible based on PD-1 immunohistochemistry (IHC). We aimed to evaluate the PD-L1 (<italic>CD274</italic>) expression using highly sensitive clone 73-10 and spatial transcriptomics (ST) analysis to elucidate the role o...

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Literature Corpus work
c1ed3884-d3fc-5673-8540-e91b55061a65
DOI
10.21203/rs.3.rs-6294929/v1
Open publication

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High-Sensitivity PD-L1 Staining Using Clone 73-10 Antibody and Spatial Transcriptomics for Precise Expression Analysis in Non-Tumorous, Intraepithelial neoplasia, and Squamous Cell Carcinoma of Head and NeckDOI 10.21203/rs.3.rs-6294929/v1
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