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Article

Characterization of tumor-associated T-lymphocyte subsets and immune checkpoint molecules in head and neck squamous cell carcinoma.

Oncotarget - 4 Jul 2017

Lechner Axel, Schlößer Hans, Rothschild Sacha I, Thelen Martin, Reuter Sabrina, Zentis Peter, Shimabukuro-Vornhagen Alexander, Theurich Sebastian, Wennhold Kerstin, Garcia-Marquez Maria, Tharun Lars, Quaas Alexander, Schauss Astrid, Isensee Jörg, Hucho Tim, Huebbers Christian, von Bergwelt-Baildon Michael, Beutner Dirk

Abstract excerpt

The composition of tumor-infiltrating lymphocytes (TIL) reflects biology and immunogenicity of cancer. Here, we characterize T-cell subsets and expression of immune checkpoint molecules in head and neck squamous cell carcinoma (HNSCC). We analyzed TIL subsets in primary tumors (n = 34), blood (peripheral blood mononuclear cells (PBMC); n = 34) and non-cancerous mucosa (n = 7) of 34 treatment-naïve HNSCC patients...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28574843
DOI: 10.18632/oncotarget.17901
PMCID: PMC5546490

Genes

CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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