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Article

Metaplastic phenotype in human primary bronchiolar epithelial cells after repeated exposure to native mainstream smoke at the air-liquid interface.

Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie - 14 Jun 2017

Aufderheide Michaela, Ito Shigeaki, Ishikawa Shinkichi, Emura Makito

Abstract excerpt

3D constructs composed of primary normal differentiated human bronchiolar epithelial (NHBE) cells as mono- or co-culture in combination with normal human lung fibroblasts were exposed repeatedly at the air-liquid interface with non-lethal concentrations of mainstream cigarette smoke (4 cigarettes a day, 5days/week, 13 times repetition in total) to build up a permanent burden on the cells. Samples were taken after...

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Identifiers

PMID: 28254108
DOI: 10.1016/j.etp.2017.01.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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