Article
Association of GLOD4 with Alzheimer’s Disease in Humans and Mice
2024-06-08
Abstract excerpt
<h4>Background</h4> Glyoxalase domain containing protein 4 (GLOD4), a protein of an unknown function, is associated with Alzheimer’s disease (AD). Three GLOD4 isoforms are known. The mechanism underlying GLOD4’s association with AD was unknown. <h4>Objective</h4> To assess GLOD4’s role in the central nervous system by studying GLOD4 isoforms expression in human frontal cerebral cortical tissues from AD patients...
Topics
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- Alzheimer's disease research and treatments
- Autophagy in Disease and Therapy
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Mitochondrial Function and Pathology
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuroscience and Neuropharmacology Research
- RNA Research and Splicing
Identifiers and source
- Literature Corpus work
- 286572a6-1e8a-5192-977d-9201c8172869
- DOI
- 10.1101/2024.06.07.597934
