Back to search

Article

Diagnostic Pharmacokinetics: how brain-derived biomarkers distribute through the human body, and how this affects their diagnostic significance - the case of S100B

2022-01-19

Abstract excerpt

Blood biomarkers of neurological diseases are often employed to rule out or confirm the presence of significant intracranial or cerebrovascular pathology or for the differential diagnosis of conditions with similar presentations (e.g., hemorrhagic vs. embolic stroke). More widespread utilization of biomarkers related to brain health is hampered by our incomplete understanding of the kinetic properties, release pat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
285ba8ef-0cb0-567e-9242-e6b50b35a3bb
DOI
10.21203/rs.3.rs-1277222/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Diagnostic Pharmacokinetics: how brain-derived biomarkers distribute through the human body, and how this affects their diagnostic significance - the case of S100BDOI 10.21203/rs.3.rs-1277222/v1
Diagnostic biomarker kinetics: how brain-derived biomarkers distribute through the human body, and how this affects their diagnostic significance - the case of S100BSemantic proximity
Bi-compartmental CSF–Serum Analysis of NfL and GFAP Differentiates Central and Peripheral Pathology in Neuroinfectious DiseasesSemantic proximity
Population-based reference equations and Z-scores for blood biomarkers of neurodegenerative diseasesSemantic proximity
Targeting S100B Protein as a Surrogate Biomarker and its Role in Various Neurological DisordersSemantic proximity
S100B in neuropathologic states: The CRP of the brain?Semantic proximity
Usefulness of S100β protein in patients on antithrombotic drugs with mild traumatic brain injury: a prospective cohort study in an emergency departmentSemantic proximity
Growing role of S100B protein as a putative therapeutic target for neurological- and nonneurological-disordersSemantic proximity
Individual progression of S100 calcium binding protein beta as a surrogate for epilepsy risk (PROG-S100B): rationale and design of a meta-analysis projectSemantic proximity
Age-specific control and Alzheimer’s disease reference curves and z-scores for glial fibrillary acidic protein in bloodSemantic proximity
Modeling synthetic serum marker kinetics for monitoring deep-tissue gene expressionSemantic proximity
The canine blood-brain barrier in health and disease: focus on brain protectionSemantic proximity
A novel blood-free analytical framework for the quantification of neuroinflammatory load from TSPO PET ImagingSemantic proximity
Select a neighboring publication to make it the new centre.