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Targeting S100B Protein as a Surrogate Biomarker and its Role in Various Neurological Disorders

9 Aug 2020

Abstract excerpt

Neurological disorders (ND) are the central nervous system (CNS) related complications originated by enhanced oxidative stress, mitochondrial failure and overexpression of proteins like S100B. S100B is a helix-loop-helix protein with the calcium-binding domain associated with various neurological disorders through activation of the MAPK pathway, increased NF-kB expression resulting in cell survival, proliferation...

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PMID: 32727332
DOI: 10.2174/1570159x18666200729100427

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