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Bi-compartmental CSF–Serum Analysis of NfL and GFAP Differentiates Central and Peripheral Pathology in Neuroinfectious Diseases

2026-06-02

Abstract excerpt

<h4>Background</h4> Neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP), established biomarkers of neuroaxonal injury and astroglial pathology, are frequently only assessed in blood, which limits conclusions regarding their origin. Bi-compartmental analyses of CSF and serum may help differentiate central or peripheral origin of biomarker elevation. Moreover, studies on NfL and GFAP in disti...

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Literature Corpus work
3360acc5-e66d-512e-9a63-b40d4cc9b8d2
DOI
10.64898/2026.05.30.26354507
Open publication

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Bi-compartmental CSF–Serum Analysis of NfL and GFAP Differentiates Central and Peripheral Pathology in Neuroinfectious DiseasesDOI 10.64898/2026.05.30.26354507
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