Article

Spatially Tuned Localization of Interleukins and OX40 Agonists Enhances Synergistic Anti-Tumor Immunity

2025-05-20

Abstract excerpt

Advances in immunotherapy have revolutionized the current standard of care for cancer patients, but unfortunately, most approaches still fail to mount a robust anti-cancer effect. This is in part due to a highly immunosuppressive tumor microenvironment which has developed bio-orthogonal mechanisms of immune escape. To address this challenge, the field has turned to combination immunotherapies, but systemic adminis...

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Literature Corpus work: 282552f0-f080-5156-855c-6bcb0cfd9767
DOI: 10.1101/2025.05.15.654266

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