Article

The fitness costs and benefits of trisomy of each <i>Candida albicans</i> chromosome

2021-01-22

Abstract excerpt

Candida albicans is a prevalent human fungal pathogen. Rapid genomic change, due to aneuploidy, is a common mechanism that facilitates survival from multiple types of stresses including the few classes of available antifungal drugs. The stress survival of aneuploids occurs despite the fitness costs attributed to most aneuploids growing under idealized lab conditions. Systematic study of the aneuploid state in C....

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Literature Corpus work: 281f6f49-2df5-5bb0-b6ff-267337b3736c
DOI: 10.1101/2021.01.21.427689

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