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Aneuploid Chromosomes Are Highly Unstable during DNA Transformation of Candida albicans

22 Aug 2009

Abstract excerpt

Candida albicans strains tolerate aneuploidy, historically detected as karyotype alterations by pulsed-field gel electrophoresis and more recently revealed by array comparative genome hybridization, which provides a comprehensive and detailed description of gene copy number. Here, we first retrospectively analyzed 411 expression array experiments to predict the frequency of aneuploidy in different strains. As...

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PMID: 19700634
DOI: 10.1128/ec.00209-09

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