Article

Haplotype synthesis analysis in public reference data reveals functional variants underlying known genome-wide associated susceptibility loci

2015-09-21

Abstract excerpt

The functional mechanisms underlying disease association identified by Genome-wide Association Studies remain unknown for susceptibility loci located outside gene coding regions. In addition to the regulation of gene expression, synthesis of effects from multiple surrounding functional variants has been suggested as an explanation of hard-to-interpret associations. Here, we define filter criteria based on linkage...

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Literature Corpus work: 27dbb257-3623-5a9e-bed9-717d3f7c84c8
DOI: 10.1101/027276

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