Article

Rare variants association testing for a binary outcome when pooling individual level data from heterogeneous studies

2020-04-18

Abstract excerpt

Whole genome and exome sequencing studies are used to test the association of rare genetic variants with health traits. Many existing WGS efforts now aggregate data from heterogeneous groups, e.g. combining sets of individuals of European and African ancestries. We here investigate the statistical implications on rare variant association testing with a binary trait when combining together heterogeneous studies, de...

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Literature Corpus work: 27cee013-37dd-5fb2-91de-96376cae5d08
DOI: 10.1101/2020.04.17.047530

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