Article

TransMut: a program to predict HLA-I peptide binding and optimize mutated peptides for vaccine design by the Transformer-derived self-attention model

2021-09-30

Abstract excerpt

<title>Abstract</title> <p>Computational prediction of the interaction between human leukocyte antigen (HLA) and peptide (pHLA) can speed up epitope screening and vaccine design. Here, we develop the TransMut framework composed of TransPHLA for pHLA binding prediction and AOMP for mutated peptide optimization, which can be generalized to any binding and mutation task of biomolecules. Firstly, TransPHLA is develop...

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Literature Corpus work: 27cb79d7-1ca8-50c8-9fee-e6a6326a428c
DOI: 10.21203/rs.3.rs-785618/v1

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