Article

Epigenome-wide DNA methylation signatures associated with combined hormonal contraceptive use

2026-08-22

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Estrogens and progestogens exert widespread regulatory effects on gene and protein expression through receptor binding and epigenetic regulation. The systemic epigenetic effects of these steroids are poorly understood. Moreover, the effects of menstrual cycle phase and hormonal contraceptive use on epigenome-wide DNA methylation in relation to depressive symp...

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Literature Corpus work: 27be8b78-5926-5c25-98ff-97e86beea879
DOI: 10.21203/rs.3.rs-10760657/v1

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