Article
Impact of Hormonal Contraceptives on Cervical T-helper 17 Phenotype and Function in Adolescents: Results from a Randomized, Crossover Study Comparing Long-acting Injectable Norethisterone Oenanthate (NET-EN), Combined Oral Contraceptive Pills, and Combined Contraceptive Vaginal Rings.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 23 Oct 2020
Konstantinus Iyaloo N, Balle Christina, Jaumdally Shameem Z, Galmieldien Hoyam, Pidwell Tanya, Masson Lindi, Tanko Ramla F, Happel Anna-Ursula, Sinkala Musalula, Myer Landon, Bosinger Steven E, Gill Katherine, Bekker Linda-Gail, Jaspan Heather B, Passmore Jo-Ann S
Abstract excerpt
BACKGROUND: Adolescents in sub-Saharan Africa are at risk for human immunodeficiency virus (HIV) infection and unintended pregnancies. Observational studies suggest that injectable hormonal contraceptives (HCs) increase the HIV risk, although their effects on genital inflammation, particularly HIV-susceptible T-helper 17 (Th17) cells, are unknown. In a randomized crossover study, the effect of injectable...
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