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Article

Single-cell transcriptomics reveals altered myeloid cell profiles associated with the early establishment of leishmania reservoirs

2024-02-12

Abstract excerpt

<title>Abstract</title> <p>Current drug regimens to treat visceral leishmaniasis (VL) are associated with a significant frequency of infection relapses, particularly in immunosuppressed patients. Understanding the cellular and tissue-specific persistence of <italic>Leishmania infantum</italic> post-treatment is crucial for improving therapeutic outcomes. Using a rhesus macaque model of VL, despite the administrat...

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Literature Corpus work
27aebc53-c1fb-530b-9597-21944320bd6b
DOI
10.21203/rs.3.rs-3931457/v1
Open publication

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Single-cell transcriptomics reveals altered myeloid cell profiles associated with the early establishment of leishmania reservoirsDOI 10.21203/rs.3.rs-3931457/v1
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