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Matrix Metalloproteinases in Non-Neoplastic Disorders

21 Jul 2016

Abstract excerpt

The matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases belonging to the metzincin superfamily. There are at least 23 members of MMPs ever reported in human, and they and their substrates are widely expressed in many tissues. Recent growing evidence has established that MMP not only can degrade a variety of components of extracellular matrix, but also can cleave and activate various non-matrix...

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PMID: 27455234
DOI: 10.3390/ijms17071178

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