Article

TGF-β2/OPTN/FOXC1/ <i>miR-200</i> axis regulates intraocular pressure dynamics in trabecular meshwork cells

2024-06-06

Abstract excerpt

<h4>Summary</h4> Glaucoma is the second leading cause of irreversible blindness globally, with elevated intraocular pressure (IOP) being its primary risk factor. Current therapeutic approaches, such as beta-blockers, alpha-adrenergic agonists, Rho-kinase inhibitors, etc., aim to reduce IOP levels. However, the molecular mechanisms underlying altered IOP remain poorly understood. In this study, we have treated pri...

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Literature Corpus work: 279a8f7b-5a3f-5457-a007-b9b109a78567
DOI: 10.1101/2024.06.06.593675

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