Article

Altered expression of exosomal miRNAs from primary human trabecular meshwork cells induced by transforming growth factor-β2

2020-05-08

Abstract excerpt

<title>Abstract</title> <p>Background Primary open-angle glaucoma (POAG) is tightly related with extracellular matrix (ECM) remodeling of human trabecular meshwork cells (HTMCs). Transforming growth factor-β2 (TGF-β2) can induce ECM remodeling. MicroRNAs (miRNAs) serve as a potential therapeutic target in influencing the development of glaucoma by regulating TGF-β2. Recent studies also have found that exosomes m...

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Literature Corpus work: dc41e8eb-92cc-5bda-8260-d15dfb92229c
DOI: 10.21203/rs.3.rs-23758/v1

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