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The artemisinin-induced dormant stages of <i>Plasmodium falciparum</i> exhibit hallmarks of cellular senescence and drug resilience

2023-01-30

Abstract excerpt

Recrudescent infections with human malaria parasite, Plasmodium falciparum , presented traditionally the major setback of artemisinin-based monotherapies. Although introduction of artemisinin combination therapies (ACT) largely solved the problem, the ability of artemisinin to induce dormant parasites still poses major obstacle for current as well as future malaria chemotherapeutics. Here, we developed a robust l...

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Literature Corpus work
278cc466-955a-557b-b1bc-3844d55f9b29
DOI
10.1101/2023.01.29.526019
Open publication

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The artemisinin-induced dormant stages of <i>Plasmodium falciparum</i> exhibit hallmarks of cellular senescence and drug resilienceDOI 10.1101/2023.01.29.526019
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