Article
Phenotypic changes in artemisinin-resistant Plasmodium falciparum lines in vitro: evidence for decreased sensitivity to dormancy and growth inhibition.
Antimicrobial agents and chemotherapy - 1 Jan 2012
Teuscher Franka, Chen Nanhua, Kyle Dennis E, Gatton Michelle L, Cheng Qin
Abstract excerpt
The appearance of Plasmodium falciparum parasites with decreased in vivo sensitivity but no measurable in vitro resistance to artemisinin has raised the urgent need to characterize the artemisinin resistance phenotype. Changes in the temporary growth arrest (dormancy) profile of parasites may be...
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