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New Potential Metabolic Biomarker and Its Role in PDAC: Insights from Genome-Wide Association Studies and Single-cell Analysis

2025-05-22

Abstract excerpt

<title>Abstract</title> <p>Background Pancreatic ductal adenocarcinoma (PDAC), a perilous malignancy, possesses a complex and largely nebulous etiology, prompting an urgent call to elucidate its underlying mechanisms and define reliable early detection biomarkers. Objective To pinpoint metabolic biomarkers causally linked to PDAC and exploring potential mechanisms. Methods We employed a two-sample mendelian ra...

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Literature Corpus work
2776ec7a-86e7-5110-bc79-6bb9d2e5a195
DOI
10.21203/rs.3.rs-6697879/v1
Open publication

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