Article
The exposome and pancreatic cancer, lifestyle and environmental risk factors for PDAC.
Seminars in cancer biology - 1 Aug 2025
Peduzzi Giulia, Archibugi Livia, Farinella Riccardo, Ponz de Leon Pisani Ruggero, Vodickova Ludmila, Vodicka Pavel, Kraja Bledar, Sainz Juan, Bars-Cortina David, Daniel Neil, Silvestri Roberto, Uysal-Onganer Pinar, Landi Stefano, Dulińska-Litewka Joanna, Comandatore Annalisa, Campa Daniele, Hughes David J, Rizzato Cosmeri
Abstract excerpt
Pancreatic cancer (PC), particularly pancreatic ductal adenocarcinoma (PDAC), is a significant global health issue with high mortality rates. PDAC, though only 3 % of cancer diagnoses, causes 7 % of cancer deaths due to its severity and asymptomatic early stages. Risk factors include lifestyle choices, environmental exposures, and genetic predispositions. Conditions like new-onset type 2 diabetes and chronic...
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