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Article

HBGA binding modes and selectivity in noroviruses upon mutation: a docking and molecular dynamics study.

Journal of molecular modeling - 28 Nov 2019

Kocak Abdulkadir

Abstract excerpt

Norovirus, also called winter vomiting bug, is the most common cause for gastroenteritis and severe childhood diarrhea disease. High mutation rates cause drug resistance and thus complicate the development of an effective therapeutics against virus infection. The virus protein enters the host cell via the interaction with histo-blood group antigens (HBGAs), formed by oligosaccharides. To date, the crystal...

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Identifiers

PMID: 31781987
DOI: 10.1007/s00894-019-4261-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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