Article

In Silico Development and Assessment of Hybrid Antimalarials as Falcipain Inhibitors

2026-06-28

Abstract excerpt

<title>Abstract</title> <p> Background Malaria, caused by protozoan parasites of the genus <italic>Plasmodium</italic> , remains one of the most consequential infectious diseases globally, with <italic>Plasmodium falciparum</italic> responsible for the majority of severe cases and deaths, particularly in sub-Saharan Africa. Falcipain, a cysteine protease central to haemoglobin degradation within infected er...

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Literature Corpus work: 1b1f61ac-caf0-5363-be35-0d8410636fb5
DOI: 10.21203/rs.3.rs-9781730/v1

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